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Nephropathies and Kidney Disease

New Protocol Streamlines Therapy That Makes More Kidney Transplants Possible

July 2008 - A new therapy developed at Cedars-Sinai Medical Center improves transplant rates and outcomes for patients awaiting living- and deceased-donor kidney transplantation, according to a study published in the July 17 issue of the New England Journal of Medicine.

The therapy may provide an option for many patients "sensitized" to transplant antigens (human leukocyte antigens, or HLA) who previously would not have been candidates for transplantation because of their intense immune response to these HLA targets.

Statins Linked to Improved Survival in Kidney Transplant Recipients

July 2008 - For patients receiving kidney transplants, treatment with cholesterol-lowering "statin" drugs may lead to longer survival, reports a study in the November 2008 Journal of the American Society of Nephrology (JASN).

Drug Lowers Body's Set Point to Control Hyperparathyroidism in Dialysis Patients

July 2008 - A medication called cinacalcet, an important part of treatment to control high levels of parathyroid hormone (PTH) in patients receiving dialysis for end-stage renal disease (ESRD), works by resetting the balance between calcium and PTH levels, according to a study in the November Journal of the American Society of Nephrology (JASN).

Drug Therapy Found Effective in Patients with Common Form of Kidney Disease

August 2008 - The drug rituximab causes considerable kidney injury healing in patients with membranous nephropathy, a common form of kidney disease, according to a study appearing in the November 2008 issue of the Clinical Journal of the American Society Nephrology (CJASN). The results suggest that this condition, previously destined to progress to kidney failure in 30-40 percent of cases, can actually be healed in some patients.

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